TP53 mutation research focuses on studying mutations in the TP53 gene, which is known as the "guardian of the genome" due to its role in regulating cell division and preventing the formation of tumors. Mutations in the TP53 gene are commonly found in various types of cancer and have been linked to tumor development, progression, and treatment resistance. Researchers study TP53 mutations to understand their impact on cancer development, identify potential therapeutic targets, and develop personalized treatment strategies for patients with TP53-mutated cancers. The ultimate goal of TP53 mutation research is to improve cancer diagnosis, treatment, and patient outcomes.